MS Clinical Companion
iOS app by ATIF ELNIL. Medical · ATIF ELNIL
- Store rating
- 0 / 5
- Store rating count
- 0
- Download price
- 14.99 USD
- In-app purchases
- Unknown
- Version
- 1.0
- Listing last refreshed
- 2026-09-10
View the original store listing
Store description excerpt
IMPORTANT: This app is intended for use by qualified healthcare professionals only. Always seek the advice of a qualified clinician before making any medical or prescribing decisions. MS Clinical Companion is a comprehensive evidence-based reference for the diagnosis and management of multiple sclerosis. Built for neurologists, MS specialist nurses, general physicians, and allied health professionals. MS DIAGNOSIS - McDonald 2017 criteria: dissemination in space (DIS) and dissemination in time (DIT) - DIS: 4 MS-typical MRI locations - periventricular, cortical, infratentorial, spinal cord - DIT: 4 methods including CSF oligoclonal bands substituting for DIT (2017 update) - MRI protocol: T2 FLAIR, gadolinium, black holes, Dawson fingers, cord imaging - MRI lesion features: open ring sign, lesion size, enhancement patterns - CSF: oligoclonal bands 85-95% sensitivity, IgG index, cell count interpretation - VEP: P100 latency, subclinical optic neuritis detection - Differential diagnosis table: NMOSD, MOG antibody disease, CNS vasculitis, neurosarcoidosis, CADASIL, B12 deficiency, Susac syndrome, Sjogren syndrome - Minimum blood tests at MS diagnosis including AQP4-IgG and MOG-IgG MS PHENOTYPES - Classification table: CIS, RIS, RRMS, SPMS, PPMS per Lublin 2013 - CIS conversion risk - RIS: ARISE 2023 trial - SPMS vs PPMS - Active vs inactive phenotypes and treatment implications RELAPSE MANAGEMENT - Relapse definition - IV methylprednisolone 1g for 3-5 days - Maximum 3 steroid courses per year with bone protection guidance - Plasma exchange: - PE protocol: 5-7 sessions - When not to treat: DISEASE MODIFYING THERAPIES - Three-tier efficacy framework - DMT comparison table - Low/moderate DMTs. - High-efficacy Drugs - JC virus risk stratification - PML recognition and management - DMT selection algorithm - Highly active RRMS first presentation SYMPTOM MANAGEMENT - Fatigue: primary vs secondary, FSS assessment, amantadine, modafinil, energy conservation - Spasticity step-ladder - Bladder: OAB vs retention vs DSD table, oxybutynin, solifenacin, mirabegron, desmopressin, ISC - Detrusor botulinum toxin: NICE approved, post-void residual guidance - Pain: trigeminal neuralgia, central dysaesthesia, Lhermitte phenomenon, painful tonic spasms - Cognition: BICAMS assessment, avoid anticholinergics, cognitive rehabilitation - Depression: SSRIs, CBT, elevated suicide risk in MS - Fampridine (Fampyra): 25-foot walk test criteria, NICE approval MS EMERGENCIES - Tumefactive MS - Acute transverse myelitis: MS vs NMOSD distinction, plasma exchange, respiratory monitoring - Marburg variant and Balo concentric sclerosis - Severe relapse PROGNOSTIC FACTORS - Poor prognostic features - NEDA-3 and NEDA-4 - PIRA significance - Serum neurofilament light chain (sNfL) as biomarker of neurodegeneration PREGNANCY AND MS - Trimester-by-trimester disease activity - Postpartum rebound - DMT safety table - Teriflunomide and fingolimod contraindication and washout protocols
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