Medicinal Chemistry
Android app by StudyZoom. Education · StudyZoom
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- Unknown
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- Free to download
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- Version
- 1.3
- Listing last refreshed
- 2026-09-11
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Store description excerpt
📘 Medicinal Chemistry (2026–2027 Edition) 📗 Medicinal Chemistry (2026–2027 Edition) is a comprehensive, research-oriented textbook designed for students & learners of pharmaceutical sciences, chemistry, life sciences, & drug discovery-related disciplines. This book provides structured coverage of medicinal chemistry with a strong focus on drug design, drug action, pharmacokinetics, toxicology, & modern drug development strategies. The content is written in clear academic English & is suitable for exam preparation, conceptual understanding, & advanced learning in medicinal chemistry. It bridges chemistry, pharmacology, & biology to explain how drugs are discovered, optimized, evaluated, & safely used in clinical practice. Unit 1: Introduction to Medicinal Chemistry • Definition & scope of medicinal chemistry • Historical development & evolution of medicinal chemistry • Role of medicinal chemistry in drug discovery & development • Interdisciplinary nature: chemistry, pharmacology, & biology Unit 2: Drug Discovery & Development Process • Stages of drug discovery & target identification • Lead discovery & lead optimization • Preclinical studies: pharmacokinetics, pharmacodynamics, & toxicity • Clinical trials: Phase I, II, III, & IV • Regulatory affairs & drug approval processes Unit 3: Principles of Drug Action • Drug–receptor interactions & binding mechanisms • Structure–activity relationships • Pharmacodynamics & pharmacokinetics • ADME: absorption, distribution, metabolism, & excretion Unit 4: Chemical Properties of Drugs • Physical & chemical properties influencing drug action • Acid–base behavior, solubility, & partition coefficient • Stereochemistry in drug action: chirality & isomerism • Prodrugs & drug delivery systems • Drug stability & formulation fundamentals Unit 5: Enzyme Inhibitors & Receptor Ligands • Competitive, non-competitive, & uncompetitive inhibitors • Mechanisms of enzyme inhibition • Agonists, antagonists, partial agonists, & inverse agonists • Allosteric modulation of receptors • Clinically important enzyme inhibitors & receptor ligands Unit 6: Medicinal Chemistry of Major Drug Classes – Part I • Antibiotics: classification, mechanisms, & resistance • Antiviral & antifungal agents • Anti-inflammatory & analgesic drugs • Cardiovascular drugs: antihypertensives & anti-arrhythmics Unit 7: Medicinal Chemistry of Major Drug Classes – Part II • CNS agents: sedatives, hypnotics, antidepressants, antipsychotics • Anticancer drugs: alkylating agents, antimetabolites, natural products • Hormones & hormone antagonists • Immunomodulators & immunosuppressants • Gastrointestinal drugs Unit 8: Drug Metabolism & Pharmacokinetics • Phase I & Phase II metabolic reactions • Cytochrome P450 enzyme system • Factors influencing drug metabolism • Pharmacokinetic parameters & models • Drug–drug interactions Unit 9: Structure-Based Drug Design • Principles of rational drug design • Computer-aided drug design (CADD) • Molecular modeling
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